Compare Atorvastatin vs Simvastatin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Statins include atorvastatin (Lipitor), fluvastatin (Lescol XL), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor, Ezallor) and simvastatin (Zocor, FloLipid). Recommended high intensity statins are atorvastatin 40mg or 80mg. In a planned switch, the target group are usually taking low-dose atorvastatin and are switched to simvastatin 40 mg as the minimum standard of treatment. Savvy Statin Shopping; Atorvastatin rated 4.4/10 vs Simvastatin rated 5.0/10 in overall patient satisfaction. Ideally, patients should give informed consent and a consistent approach to patient choice should ensure that patients are aware that the reason the switch is being undertaken is to promote better use of healthcare resources. Switching From Simvastatin 80 mg: How to Shop for Statins - Medscape - Aug 12, 2011. In patients already on simvastatin 40mg for secondary prevention, review to uptitrate to atorvastatin 80mg or 40mg if more appropriate. Statins have potentially serious side effects, and there are instances in which they should not be taken. The side effects you're experiencing are definitely good enough reason for your doctor to consider switching you to either different statin medication - simvastatin or perhaps some of the newer statins, or some other cholesterol lowering medication. Where patients are already stable on simvastatin 80mg this may be continued if preferred. Having too much cholesterol in your blood increases your risk of heart attacks and strokes. lovastatin pravastatin simvastatin % ldl reduction (mevacor*) (pravachol*) (zocor*) lescol lipitor crestor vytorin 25-32% 20 mg 20mg 10mg 40mg - - - 31-39% 40mg 40mg 20mg 80mg 10mg - - 37-45% 80mg 80mg 40mg - 20mg 5mg 10/10