Liver transplant may also be an option if the tumor is in a part of the liver that … It could also mean that you have serious medical problems that make surgery unsafe. Learn more about these partnerships and how you too can join us in our mission to save lives, celebrate lives, and lead the fight for a world without cancer. American Cancer Society medical information is copyrighted material. All rights reserved worldwide. Primary liver cancer begins in the liver. Fong Y, Dupey DE, Feng M, Abou-Alfa G. Ch. If surgery is done, the pathologic stage (also called the surgical stage) is determined by examining tissue removed during an operation. Doctors also use a cancer's stage when talking about survival statistics. If you have questions about the stage of your cancer or which system your doctor uses, be sure to ask. Our team of expert journalists brings you all angles of the cancer story – from breaking news and survivor stories to in-depth insights into cutting-edge research. It might or might not have spread to nearby lymph nodes (any N). A single tumor larger than 2cm (4/5 inch) that hasn't grown into blood vessels (T1b). This type of cancer is named after the organ in which it began — such as metastatic colon cancer to describe cancer that begins in the colon and spreads to the liver. This section describes the stages of primary liver cancer. Stage IIIB: The cancer has spread to one of the main blood vessels in the liver (the portal or hepatic veins), but it has not reached the lymph nodes or other organs. This system looks at 5 factors, the first 3 of which are results of blood tests: Based on these factors, there are 3 classes of liver function. American Joint Committee on Cancer. Very early stage. We’ve invested more than $4.9 billion in cancer research since 1946, all to find more – and better – treatments, uncover factors that may cause cancer, and improve cancer patients’ quality of life. A higher number, such as stage IV, means cancer has spread more. Metastatic (secondary) liver cancer is cancer that has spread from another part of the body to the liver. Some are used more than others in different parts of the world, but at this time there is no single staging system that all doctors use. This section describes the stages of primary liver cancer. Cancer.org is provided courtesy of the Leo and Gloria Rosen family. Staging a cancer helps determine the prognosis of the disease, which is the chance of recovery, and the types of treatment that are most appropriate. The staging system most often used in the United States for liver cancer is the AJCC (American Joint Committee on Cancer) TNM system, which is based on 3 key pieces of information: The system described below is the most recent AJCC system, effective January 2018. Although it can occur at any stage of liver failure, people with cirrhosis are at an increased risk for developing liver cancer. The BCLC system categorizes HCC based on characteristics of the tumor, liver function, performance status, and cancer-related symptoms. The stage of a cancer tells you its size and whether it has spread. Although each person’s cancer experience is unique, cancers with similar stages tend to have a similar outlook and are often treated in much the same way. 57 - Cancer of the Liver. These would include stages IVA and IVB cancers in the TNM system. © 2020 American Cancer Society, Inc. All rights reserved. Advanced stage. Liver function varies. If the cancer has metastasized, that means it has spread outside of the liver. Together, we’re making a difference – and you can, too. The staging systems for most types of cancer depend only on the extent of the cancer, but liver cancer is complicated by the fact that most patients have damage to the rest of their liver along with the cancer. The tests and scans you have to diagnose your cancer give some information about the stage. . Available Every Minute of Every Day. There may be no increased pressure in the portal vein, increased portal vein pressure and normal bilirubin levels, or increased portal vein pressure and increased bilirubin levels. Doctors also use a cancer's stage when talking about survival statistics. This also affects treatment options and survival outlook. Early stage. 11th ed. Until we do, we’ll be funding and conducting research, sharing expert information, supporting patients, and spreading the word about prevention. More than one tumor, with at least one tumor larger than 5 cm across (T3). Liver cancer stages range from stage I (1) through IV (4). Imagine a world free from cancer. 77 - Liver and Bile Duct Cancer. From basic information about cancer and its causes to in-depth information on specific cancer types – including risk factors, early detection, diagnosis, and treatment options – you’ll find it here. NCCN Clinical Practice Guidelines in Oncology: Hepatobiliary Cancers. Making Strides Against Breast Cancer Walks, Common Questions About the COVID-19 Outbreak. Primary liver cancer begins in the liver. Often this is because the non-cancerous part of your liver is not healthy (because of cirrhosis, for example), and if the cancer is removed, there might not be enough healthy liver tissue left for it to function properly.